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In addition to shared genes, they found that Li exposure was associated with 554 genes enriched for OXPHOS pathways and thermogenesis (Osete et al., 2021)

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Overexpression of LAMP3 disrupts lysosomal membranes by degrading LAMP1, leading to lysosomal dysfunction and impaired autophagy [278]

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Barretts Esophagus A serious condition in which the lining of the esophagus changes due to chronic acid exposure, Barretts esophagus is considered a risk for esophageal cancer

Exenatide and dulaglutide exhibited no meaningful change in risk